We must remember that one determined person can make a significant difference, and that a small group of determined people can change the course of history.
Sonia Johnson

We need affordable space travel to inspire our youth, to let them know that they can experience their dreams, can set significant goals and be in a position to lead all of us to future progress in exploration, discovery and fun. Thanks to the X Prize for the inspiration.
Burt Rutan

We saw in 2003 the beginnings of an outbreak of an illness called SARS. SARS ended up killing 800 people which is a significant number of deaths, but nowhere near as high as it could have been.
Michael Burgess

We went around and looked and talked to a lot of foundations with those charities and decided upon the Children's Hospital. They had a golf tournament at the time, but it was a small event that didn't raise a significant amount of money.
Tom Kite

We, as a country, have not seen a significant change in immigration policy in nearly two decades, even though all Americans agree that current immigration policy is outdated and malfunctioning.
Raul Grijalva

We're involved right now in some very significant legal battles and it would be the wrong thing for me to do to step out in the middle of those battles.
Bill Scott

We've already gotten a significant grant from the Andrew W. Mellon Foundation, and a university consortium. I think the whole sector of Foundations, potentially with government support, is promising - more than promising, I think, it's substantial.
Mitch Kapor

What I had said in the morning was that this is what we know has happened, but there has been no significant off-site release. Only to find out moments later that, in fact, there had been an off-site release. I still haven't gotten over that.
William Scranton

What is right? Simply put, it is any assignment in which the photographer has a significant spiritual stake... spiritually driven work constitutes the core of a photographer's contribution to culture.
William Albert Allard

What was most significant about the lunar voyage was not that men set foot on the moon but that they set eye on the earth.
Norman Cousins

What's happened with society is that we have created these devices, computers, which already can register and process huge amounts of information, which is a significant fraction of the amount of information that human beings themselves, as a species, can process.
Seth Lloyd

When I handed over the names and compromised so many CIA agents in the Soviet Union, I had come to the conclusion that the loss of these sources to the U.S. would not compromise significant national defense, political, diplomatic interests.
Aldrich Ames

When looking at any significant work of art, remember that a more significant one probably has had to be sacrificed.
Paul Klee

When police or prosecutors conceal significant exculpatory or impeaching material, we hold, it is ordinarily incumbent on the state to set the record straight.
Ruth Bader Ginsburg

When the satisfaction or the security of another person becomes as significant to one as one's own satisfaction or security, then the state of love exists. Under no other circumstances is a state of love present, regardless of the popular usage of the term.
Harry Stack Sullivan

When trying to remember my share in the glow of the eternal present, in the smile of God, I return to my childhood, too, for that is where the most significant discoveries turn up.
Herman Hesse

When you look at other countries that are developing the capabilities and the technology to deploy missiles of very significant destructive capability with nuclear, chemical, or biological warheads, then the MAD dogma makes even less sense.
Don Nickles

When you talk about evangelicals, don't forget that a significant proportion of the evangelical community is African American. And most African Americans - well over 90 percent, thoroughly evangelical, thoroughly biblical - will probably vote Democratic.
Tony Campolo

While all of these are important and significant events, it is the United States' foreign policy that furthers the advancement of freedoms and rights for women that is the most striking for me.
Ginny B. Waite

Whitesnake more than most rock bands would get a very significant percentage of women in the audience and those were the ones I'd hear the voices because from where I am on stage is a pretty good spot.
David Coverdale