A blank wall of social and professional antagonism faces the woman physician that forms a situation of singular and painful loneliness, leaving her without support, respect or professional counsel.
Elizabeth Blackwell

A lot of people have gotten into comedy because of certain influences in their lives or events that were painful, and I really have wracked my brain to figure it out. I pretty much have had a normal childhood. Maybe it was too normal.
Will Ferrell

All our knowledge merely helps us to die a more painful death than animals that know nothing.
Maurice Maeterlinck

Alzheimer's is a devastating disease. It was painful for me and my family to watch my grandfather deteriorate. We must find a cure for this horrible disease.
David Hyde Pierce

And in this respect, the Israeli-Palestinian conflict has been a tragedy, a clash between one very powerful, very convincing, very painful claim over this land and another no less powerful, no less convincing claim.
Amos Oz

And the day came when the risk to remain tight in a bud was more painful than the risk it took to blossom.
Anais Nin

As to those who hoard gold and silver and spend it not in God's path, give them, then, the tidings of a painful agony: on a day when these things shall be heated in hell-fire, and their foreheads, and their sides, and their backs shall be branded therewith.
Kin Hubbard

At painful times, when composition is impossible and reading is not enough, grammars and dictionaries are excellent for distraction.
Elizabeth Barrett Browning

At that time, I had recently finished a book called Amazing Grace, which many people tell me is a very painful book to read. Well, if it was painful to read, it was also painful to write. I had pains in my chest for two years while I was writing that book.
Jonathan Kozol

Be the business never so painful, you may have it done for money.
Thomas Fuller

Black people were very angry with me for writing the book. A lot of people didn't believe me, or didn't want to believe me, and that used to really bother me. It was a very painful and difficult time.
LaToya Jackson

Breaking with old friends is one of the most painful of the changes in all that piling up of a multitude of small distasteful changes that constitutes growing older.
John Dos Passos

But for me, it is when a student has died. I find the death of a young person the most difficult and painful of times. To explain it to other young people, to see a bright future snuffed out, is just awful. I am haunted by those deaths.
Donna Shalala

But I don't write so much now, because they're too painful.
Bryan Ferry

But I've never considered myself any kind of heartthrob. It sounds painful.
Gavin DeGraw

But my experience is that people who have been through painful, difficult times are filled with compassion.
Amy Grant

But through world wars and a Great Depression, through painful social upheaval and a Cold War, and now through the attacks of September 11, 2001, our Nation has indeed survived.
Nick Rahall

But what we call our despair is often only the painful eagerness of unfed hope.
George Eliot

Catholicism is not a soothing religion. It's a painful religion. We're all gluttons for punishment.
Madonna Ciccone

Collaboration is no longer painful - or precious.
Vince Clarke