The hardest problems of pure and applied science can only be solved by the open collaboration of the world-wide scientific community.
Kenneth G. Wilson

The hardest situation to stay happy in, I think, is when you're trying to find love, and yourself at the same time. It just doesn't seem to fit well.
Sophia Bush

The hardest struggle of all is to be something different from what the average man is.
Robert H. Schuller

The hardest task in a girl's life is to prove to a man that his intentions are serious.
Helen Rowland

The hardest that I've laughed at a movie was probably Team America. I laughed 'til I thought I was just gonna throw up. I almost had to turn it off.
Ron White

The hardest thing about any political campaign is how to win without proving that you are unworthy of winning.
Adlai E. Stevenson

The hardest thing about being James Brown is I have to live. I don't have no down time.
James Brown

The hardest thing about having three kids is trying to find a balance, because there's always the odd man out, and you also need to make sure each child gets the attention he or she needs.
Patrick Dempsey

The hardest thing about movie acting is that if you're playing a character who changes within the movie, you've got to do that, but you've got to do it out of sequence, because we never have gotten to shoot in sequence, and that's really, really tough.
John Sayles

The hardest thing for me is not to keep laughing. Jennifer particularly is like a clown.
Victor Garber

The hardest thing I had to overcome in life? I think racism. That's so difficult because I don't think anyone can ever understand it. It's not that people don't want to understand it, but they don't want to touch it.
Herschel Walker

The hardest thing in life to learn is which bridge to cross and which to burn.
David Russell

The hardest thing in my industry is longevity, getting your next job. It's hard to get the first job, but it's so much harder to get the sixth or seventh as a woman.
Anna Faris

The hardest thing is at the end you have to say bye to all these people who you have worked with for so many months. It was really sad not to see them anymore. But you have the parties that you go to and you get to see them, like the premieres and the screenings.
Dakota Fanning

The hardest thing is the idea. Ideas come from somewhere but as far as we know they come from nowhere.
Ian Hunter

The hardest thing is to go to sleep at night, when there are so many urgent things needing to be done. A huge gap exists between what we know is possible with today's machines and what we have so far been able to finish.
Donald Knuth

The hardest thing is to take less when you can get more.
Kin Hubbard

The hardest thing is trying not to correct everything on the Internet. It'd be night and day - wrong, wrong, wrong, wrong. So you just have to say, 'All right, I'll take it, bring it on.'
George Clooney

The hardest thing to believe about The Fan is not that Robert De Niro is stalking somebody again but that anyone cares that much about a baseball player.
Bernie Lincicome

The hardest thing to explain is the glaringly evident which everybody had decided not to see.
Ayn Rand