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The ever quickening advances of science made possible by the success of the Human Genome Project will also soon let us see the essences of mental disease. Only after we understand them at the genetic level can we rationally seek out appropriate therapies for such illnesses as schizophrenia and bipolar disease.
James D. Watson
Cancer is a disease of the genome. And that's what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should've stopped, and that's cancer. And those mistakes are mistakes of DNA.
We live in a dancing matrix of viruses; they dart, rather like bees, from organism to organism, from plant to insect to mammal to me and back again, and into the sea, tugging along pieces of this genome, strings of genes from that, transplanting grafts of DNA, passing around heredity as though at a great party.
The brain is the most complicated organ in the universe. We have learned a lot about other human organs. We know how the heart pumps and how the kidney does what it does. To a certain degree, we have read the letters of the human genome. But the brain has 100 billion neurons. Each one of those has about 10,000 connections.
It will be the mother of all telescopes, and you can bet it will do for astronomy what genome sequencing is doing for biology. The clumsy, if utilitarian, name of this mirrored monster is Large Synoptic Survey Telescope, or LSST. You can't use it yet, but a peak in the Chilean Andes has been decapitated to provide a level spot for placement.
Eventually we'll be able to sequence the human genome and replicate how nature did intelligence in a carbon-based system.
Human experience depends on everything that can influence states of the human brain, ranging from changes in our genome to changes in the global economy.
I'm fascinated with genetic science, and I have been for a very long time. I always look at science and technology because I think that the developments in my lifetime have been so remarkable - and we're only at the tip of the iceberg with projects like decoding the human genome.
Genome design is going to be a key part of the future. That's why we need fast, cheap, accurate DNA synthesis, so you can make a lot of iterations of something and test them.
If we can put a man on the moon and sequence the human genome, we should be able to devise something close to a universal digital public library.
As a Christian, but also as a scientist responsible for overseeing the Human Genome Project, one of my concerns has been the limits on applications of our understanding of the genome. Should there be limits? I think there should. I think the public has expressed their concern about ways this information might be misused.
From the growth of the Internet through to the mapping of the human genome and our understanding of the human brain, the more we understand, the more there seems to be for us to explore.
We can't any longer have the conventional understanding of genetics which everybody peddles because it is increasingly obvious that epigenetics - actually things which influence the genome's function - are much more important than we realised.
Your genome knows much more about your medical history than you do.
W. Daniel Hillis
The food we eat goes beyond its macronutrients of carbohydrates, fat and protein. It's information. It interacts with and instructs our genome with every mouthful, changing genetic expression.
If you look on the fungal genome as being soldier candidates protecting the U.S. as our host defense, not only for the ecosystem but for our population... we should be saving our old-growth forests as a matter of national defense.
Medicine will be personalized and preventive: Your genome might predict that you have an 80 percent chance of breast cancer by the time you are 50, but if you take a preventive drug starting when you are 40, the chance will drop to 2 percent.
It's terrifying the way molecular biology has become more and more jargon ridden. But I strongly believe that my book can be read by the intelligent layman. I want everyone who bought a copy of 'A Brief History of Time' to buy a copy of 'Genome'.
Though social eugenics was discredited long ago, we still often think of the genome in quasi-eugenic terms. When we read about the latest discovery of a link between a gene and a disease, we imagine that we've learned the cause of the disease, and we may even think we'll get a cure by fixing the gene.
If you go far enough back, your genome connects you with bacteria, butterflies, and barracuda - the great chain of being linked together through DNA.
It turns out that viruses evolve from each other, like everything else. So if you look at the evolutionary tree of viruses, you can find parts of their genome that haven't changed over evolutionary time. You can recognize what may be a new virus by identifying this little piece of their genome that hasn't changed and is represented on the chip.
Why do people believe that there are dangerous implications of the idea that the mind is a product of the brain, that the brain is organized in part by the genome, and that the genome was shaped by natural selection?
People think if you have deciphered the genome of humans that you can change everything. But you cannot change everything, because you do not know what the genes mean, and you have no methods for changing them, and you can't do experiments with humans like you can with animals.
Genome sequencing has changed taxonomy.
Heritability pertains to the entirety of the genome, not to a single gene.
Martin Luther King, Jr.
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